Section Handout #4

Section Handout #4 - hannashim@gmail.com OH: Tuesdays @ 4PM...

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hannashim@gmail.com OH: Tuesdays @ 4PM @ Café Roma BIPN 100 Hand-Out #4 Skeletal Muscle Smooth Muscle Cardiac Muscle Striated/Has Sarcomeres Yes No Yes (for Contractile fibers) No (for Pacemaker fibers) Fibers Have a Single Nucleus No Yes Yes Electrically Linked/Has Gap Jxns No Yes (for Unitary) No (for Multifiber) Yes Neurogenic/ Myogenic Neurogenic Myogenic (for Unitary) Neurogenic (for Multifiber) Myogenic (for both Pacemaker and Contractile Cells) NOTE: Contractile Cells are innervated only by the SYMPATHETIC nervous system How Sarcoplasmic Reticulum Is Opened DHP receptor on the T- tubule activates the RyR on the sarcoplasmic reticulum, allowing Ca2+ efflux SR = less functionally significant than for skeletal and cardiac Extracellular Ca2+ binds to the RyR on the sarcoplasmic reticulum, allowing Ca2+ efflux (Calcium-Induced Calcium Release) Source of Ca2+ for Contraction Sarcoplasmic Reticulum Extracellular [Ca2+] Extracellular [Ca2+] & Sarcoplasmic Reticulum Ca2+ Binds To Troponin Calmodulin Troponin Relaxation Ca2+-ATPase (on the Sarcoplasmic Reticulum) 1.Ca2+-ATPase (on the sarcolemma) 2.Ca2+-Na+ antiport (on the sarcolemma)
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This note was uploaded on 07/14/2009 for the course BIPN BIPN 100 taught by Professor French during the Spring '08 term at UCSD.

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Section Handout #4 - hannashim@gmail.com OH: Tuesdays @ 4PM...

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