Class 06 CNS2 - Central Nervous System, II Localization of...

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Unformatted text preview: Central Nervous System, II Localization of Function Class #6 September 23, 2008 Todays outline Techniques to study representation of the body surface in the spinal cord and brain Herpes infections Wilder Penfield and The Homunculus Strokes and Brain injuries Prefrontal cortex - lobotomies and trepanations Split-brains Dermatomes are represented as if we were quadrapeds. Herpes Infection of Neurons HSV-1 and HSV-2: above waist/below waist. Refers to route of usual infection. Varicella-Zoster, Herpes Zoster, HV-3. Causes chicken pox usually through respiratory tract. Eventually produce blisters on epithelium. The virus may migrate to ganglion in spinal cord or brain from region of active replication, where they remain dormant. Conditions (stress, infections, sunlight) may activate the virus that migrates to the periphery resulting in blistering, searing pain, burning and even local paralysis. HSV-1,2 Infections include oral and genital Herpes Infections Bells Palsy is likely an HSV-1 infection of the facial nerve (motor nerve). Fever sore from HSV infection of trigeminal nerve (sensory nerve) Ramsey-Hunt Syndrome affects the facial nerve; causes intense pain and paralysis. Note that HSV-1 infection of the facial nerve causes Bells Palsy. Shingles infection of a thoracic dermatome HV-3 infections are common on chest, shoulder, neck, face. Some treatments for Herpes Infections Pain non-steroidal anti-inflammatory Steroids to reduce inflammation Anticonvulsants to calm excited nerves, for example, Neurontin Antiviral drugs for example, Antibiotics in case the blisters become infected Hopefully prevent Post Herpetic Neuralgia, in which case a Pain Spet is needed. Lateralization of Function In general Sensory and Motor control of:...
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Class 06 CNS2 - Central Nervous System, II Localization of...

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