Results and Discussion Exp 5

Results and Discussion Exp 5 - compounds we were testing...

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Results and Discussion Through Thin Layer Chromatography, we tested for the active ingredients in certain analgesics. After comparing the R f values of the analgesics to the ingredients that we were testing for, we were able to determine the active ingredients for Tylenol, Excedrin AF, Excedrin, and Motrin. Motrin’s only active ingredient that we discovered was Ibuprofen. Aspirin’s active ingredients are Caffeine and Acetaminophen. Tylenol’s active ingredients are Acetaminophen and Aspirin. Excedrin AF’s active ingredients are Caffeine, Acetaminophen, and Aspirin Conclusion Our detection of active ingredients in the analgesics using TLC was successful. Each Rf value (from the analgesics) directly related to an Rf value of one of the
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Unformatted text preview: compounds we were testing for. Questions 1. If a very polar solvent such as methanol was used because a good solvent would pull the various compounds to different degrees of the TLC plate. Methanol would not do this because of its high polarity; it would only pull the other very polar compounds up the TLC plate while not attracting the non-polar compounds. This best solvent would be one with an intermediate polarity. The best way to have a solvent with an intermediate polarity is to mix them. 2. If there is too much solvent in the development chamber, the solvent would dissolve the compounds before they are able to separate, yielding no results....
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