L5-Vesicle Transport

L5-Vesicle Transport - BIO320S - Lecture 5 Membrane...

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BIO320S - Lecture 5 Membrane Traffic: Vesicle Transport, Coats, Rabs & Snares
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Three Basic Players of Membrane Traffic: Donor membrane, Transport Vesicle, and Target Membrane
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Different coats form vesicles in different membrane compartments
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Vesicle budding induced by COATS that surround vesicles COATS: peripheral membrane protein function as: a mechanical device that can bend and curve a vesicle, (vesicle budding) a mechanism for selecting the cargo for the vesicle
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Three Distinct Vesicle Coats COP = coatomer protein
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COP II - Endoplasmic Reticulum COP I - Golgi Apparatus Clathrin + AP1 - TransGolgi Stack Clathrin + AP2 - Plasma Membrane Different coats form vesicles at specific locations Adaptin (AP1 or AP2) = Proteins that help Clathrin form coats in specific locations
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Clathrin triskelion Clathrin cage
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Assembly of Triskelions Into a Lattice Clathrin triskelion QuickTime™ and a Video decompressor are needed to see this picture.
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This note was uploaded on 07/22/2009 for the course BIO 89545 taught by Professor De lozanne during the Spring '09 term at University of Texas.

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L5-Vesicle Transport - BIO320S - Lecture 5 Membrane...

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