L6-ER, Golgi, Lysosome Traffic

L6-ER, Golgi, Lysosome Traffic - BIO320S Lecture 6 Membrane...

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BIO320S - Lecture 6 Membrane Traffic: Post-Translational modifications Transport from the ER through the Golgi apparatus to the Lysosome What happens to proteins in these compartments? How do proteins travel between compartments?
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Recruitment of Cargo Proteins into ER transport vesicles Alberts 13-20
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ER to Golgi Movement visualized with fluorescent secretory protein QuickTime™ and a Photo - JPEG decompressor are needed to see this picture. Nucleus Golgi ER
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Vesicular tubular clusters Alberts 13-23
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COPII coated vesicles: ER---> cis-Golgi COPI coated vesicles: cis-Golgi --> ER Karp 8.25 COPII: anterograde transport COPI: retrograde transport
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Snares need to be transported back to their original compartment for further rounds of vesicle fusion Alberts 13-18 After vesicle fusion the SNARE complex is dissociated by NSF using ATP energy. Dissociated SNARES are then transported back to their original compartment
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Resident ER Proteins can “escape” from the ER Karp 8.25
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This note was uploaded on 07/22/2009 for the course BIO 89545 taught by Professor De lozanne during the Spring '09 term at University of Texas.

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L6-ER, Golgi, Lysosome Traffic - BIO320S Lecture 6 Membrane...

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