L7-Endo and Exocytosis - BIO320S - Lecture 7-8 Membrane...

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BIO320S - Lecture 7-8 Membrane Traffic: Exocytosis Endocytosis
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There Are Two Basic Types of Exocytosis Alberts 13-63
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Exocytosis: Constitutive and Regulated paths use v-snares and t-snares (and rabs) to regulate fusion of the vesicle with the plasma membrane. Alberts 13-66
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Regulated secretion by a Mast cell: release of heparin and histamine from regulated secretory granules Alberts 13-68
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Endocytosis: 1. Phagocytosis (cell eating) 2. Pinocytosis (cell drinking) a. Macropinocytosis (actin-mediated) b. Clathrin-mediated c. Caveolin-mediated Alberts 13-2
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C aveolin-m ediated Caveolae (“little cavities”) Form from rafts on              Plasma  membrane Pinocytosis: Cavelae also bring in fluid from the plasma membrane Alberts 13-49
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Pinocytosis: Clathrin vesicles bring in fluid from the plasma membrane C lathrin-m ediated Alberts 13-48
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Endocytosis accomplished by clathrin 1. Pinocytosis: uptake of liquid by in lumen of clathrin coated vesicles 2. Receptor-Mediated Endocytosis: incorporation of receptors in bilayer of clathrin coated vesicles: signal-mediated
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Sorting Signals for Clathrin Coated Vesicles at the Plasma Membrane 1) A signal with a tyrosine 2) A di-leucine signal
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This note was uploaded on 07/22/2009 for the course BIO 89545 taught by Professor De lozanne during the Spring '09 term at University of Texas at Austin.

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L7-Endo and Exocytosis - BIO320S - Lecture 7-8 Membrane...

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