L10-Mitochondrial Transport

L10-Mitochondrial - BIO320 Lecture 10 IMPORT OF PROTEINS INTO MITOCHONDRIA*OPTIONAL READING review article K.L Adams J D Palmer(2003 Evolution of

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BIO320 - Lecture 10 IMPORT OF PROTEINS INTO MITOCHONDRIA ***OPTIONAL READING: review article*** K.L. Adams & J. D. Palmer (2003) Evolution of mitochondrial gene content: gene loss and transfer to the nucleus Molec. Phylogenet. Evol. 29:380-395 Downloadable @ blackboard
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The origin of Mitochondria and Chloroplasts Alberts 12-4
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Mitochondrial Organization Has its own: • genome • tRNA rRNA = ribosome Encodes some mitochondrial proteins Most mitochondrial proteins encoded in the nucleus See Alberts Figures 12-21 & 14-8
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Karp 5.3 The outer membrane of mitochondria and bacteria have the channel protein “porin” Allows the passage of small metabolites (H + , ions, ATP, NAD, CoA) but NOT of large proteins See Alberts Figure 10-26
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The mitochondria contains all enzymes used in the TCA cycle and oxidative phosphorylation Alberts 14-10
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The electron transport chain is a set of three proton pumps that use the energy of NADH to move protons out of the matrix Alberts 14-14
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The electron transport chain forms a proton electrochemical gradient called the Proton Motive Force Alberts 14-13
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Cooper
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This note was uploaded on 07/22/2009 for the course BIO 89545 taught by Professor De lozanne during the Spring '09 term at University of Texas at Austin.

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L10-Mitochondrial - BIO320 Lecture 10 IMPORT OF PROTEINS INTO MITOCHONDRIA*OPTIONAL READING review article K.L Adams J D Palmer(2003 Evolution of

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