Ch_322a_5.04

Ch_322a_5.04 - The History of Stereochemistry In 1874 two...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
The History of Stereochemistry In 1874 two young chemists, J.H. Van't Hoff (Utrech) and J.A. Le Bel (Sorbonne) deduced a tetrahedral geometry for tetravalent carbon from their observations of substituted methanes. The Van't Hoff and Le Bel Argument At that time, it was known that only one compound of the general formula CH 3 Y had ever been found. For example, there is only one compound with the formula CH 3 Br. This observation means that all 4 H in CH 4 are equivalent . Possible Geometries for CH 4 C H H H H C H H H H C H H H H square planar pyramidal tetrahedral
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Disubstituted Methanes Also, for the general formula CH 2 XY, there is only one known compound. For example, only one compound exists with the formula CH 2 BrCl. This observation rules out the square planar and pyramidal geometries for methane (and tetravalent carbon, in general) because stereoisomers should exist for CH 2 XY with those geometries.
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 5

Ch_322a_5.04 - The History of Stereochemistry In 1874 two...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online