Fischer Projection Formulas
Emil Fischer (18521919), one of the most prominent German
chemists of the late 19th and early 20th centuries, devised a
convention for representing threedimensional structural
information in two dimensions. These
"Fischer formulas"
are
especially helpful in keeping track of stereochemical details in
structures with more than one stereocenter.
Example: (R)2chlorobutane
C
H
Cl
CH
3
CH
2
CH
3
The TwoDimensional Fischer Formula
Draw vertical and horizontal crossing lines. The
point of intersection is the stereocenter.
The horizontal line represents bonds projected towards the
viewer.
H
Cl
The vertical line represents bonds projected away from the
viewer.
CH
2
CH
3
CH
3
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View Full DocumentHow to Use Fischer Formulas: (S,R)2,3Dibromobutane
CH
3
CHCHCH
3
Br
Br
*
*
By convention, Fischer
formulas are written with
the
main chain extending
top to bottom
.
C
C
CH
3
CH
3
Br
Br
H
H
(S,R)2,3Dibromobutane (meso)
3dimensional
representation
CH
3
CH
3
Br
Br
H
H
Fischer Formula
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 Summer '07
 Jung
 Organic chemistry, Fischer projection, Fischer Formulas

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