BIO 203 Exam 2 Form 2 2009

BIO 203 Exam 2 Form 2 2009 - BIO 203 Spring 2009 Exam 2 1...

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BIO 203 – Spring 2009 Exam 2 1 April 2009 Page 1 For all questions choose the most INCORRECT answer 1) Central nervous system (CNS): a) Due to the localization and regulation of several autonomic functions within the CNS, complete and irreversible destruction of all conscious perception through destruction of cerebral cortex is not synonymous with death, if death is defined as irreversible cardiac arrest. b) CSF is manufactured by modified ependymal cells, fills the ventricles of the brain, and because of its incompressible fluid properties serves as a ‘shock absorber’ for external strikes to the skull. c) There is a rostrocaudal sensory map of the body surface reflected in the segmental organization of sensory input to spinal cord, such that sensory information from the legs enters cervical spinal cord and sensory input from the chest enters thoracic spinal cord. d) Despite the fact that the brain is immunologically naïve, in part due to the presence of a blood-brain barrier, a primitive immunological function within brain is carried out by microglia acting as scavengers. 2) Somatic nervous system: a) While the neuronal cell bodies are located in the central nervous system within the spinal cord, the axons of the somatic nervous system are located in the peripheral nervous system. b) The neurotransmitter released in the peripheral nervous system binds to a nonspecific cation selective ligand-gated ion channel. c) Striated muscles innervated by the somatic nervous system may or may not be under voluntary control. d) Sympathetic preganglionic neuronal cell bodies are located in the central nervous system and release the same neurotransmitter as the somatic nervous system. 3) T lymphocytes: a) Cytotoxic T-cell activation requires, in part, presentation of an antigenic protein complexed with an MHC I protein on the cell surface of a virally-inflected cell. b) Cytotoxic T-cell release of cytokines requires, in part, the recognition of a CD4 protein on the surface of the cytotoxic T-cell by MHC I protein on the surface of an infected cell. c) Cytotoxic T-cell activation will result in the killing of infected cells, in part, by releasing the protein perforin which acts on the infected cell membrane in a manner similar to that of the MAC complex. d) T-helper cell activation requires, in part, presentation of an antigenic protein fragment complexed with MHC II protein on the cell surface of an APC cell. 4) Second messenger pathways: a) Increases in intracellular second messengers result from activation of membrane associated amplifier enzymes by GDP-activated G-proteins. b) Muscarine binding to an ACh receptor in the peripheral nervous system indirectly opens an ion channel despite the fact that the receptor is G-protein linked. c) Epinephrine activation of the phospholipase C pathway results in the generation of the intracellular 2
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BIO 203 Exam 2 Form 2 2009 - BIO 203 Spring 2009 Exam 2 1...

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