Unformatted text preview: trans-)halohydrin “OH-OH” OsO 4 , NMO N/A Syn (Cis) Trans-diol made from treatment of H 3 O + on epoxide Oxidation/Cleavage of alkenes C=C Reagent Result 1. O 3 2. Zn, H 3 O + Alkene carbons become carbonyls, yields aldehydes and ketones KMnO 4 , H 3 O + Alkene carbons become carbonyls, • if H is present on alkene carbon, becomes a carboxcylic acid • if 2H present, get CO 2 HIO 4 , H 2 O Cis-diols become carbonyls, yielding ketones, aldehydes • Dihydroxylation (OsO 4 , NMO), then treatment with HIO 4 is an alternative to ozonolysis...
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This note was uploaded on 07/30/2009 for the course CHEM 101 taught by Professor Williamson during the Spring '08 term at Texas A&M.
- Spring '08