abstract 2 - MRSA has now even came up in communities...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Esteban Sanchez 2/3/09 PLAN 370-500 Abstract 2 Antibiotic-Resistant Bugs in the 21st Century — A Clinical Super-Challenge In 1942 a women was dying of streptococcal sepsis, despite the efforts of medical science, her doctors could not eradicate her bloodstream infection. They then came across Penicillin. After repeated doses her bloodstream was cleared of streptococci, she made a full recovery. Sixty-six years later a report described a 70-year-old man in San Francisco with endocarditis caused by vancomycin-resistant Enterococcus faecium (VRE). Physicians of VRE were not able to clear his blood stream and head died with bacteria left in his blood stream. We have now come to a point in the 21 century where for people with multidrug resistant bacteria, there is no magic bullet. Currently methicillin-resistant Staphylococcus aureus (MRSA) and E. faecium represent the biggest therapeutic hurdles.
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: MRSA has now even came up in communities outside of the hospital. MRSA in the community is now the leading cause of identifiable skin and soft-tissue infections seen in U.S. emergency rooms. Faced with this gloomy picture, 21st-century clinicians must turn to compounds developed decades ago and previously abandoned because of toxicity — or test everything they can think of and use whatever looks active. A concerted effort on the part of academic researchers and their institutions, industry, and government is crucial if humans are to maintain the upper hand in this battle against bacteria. Citation: Cesar A. Arias, M.D., Ph.D., and Barbara E. Murray, M.D. “Antibiotic-Resistant Bugs in the 21st Century — A Clinical Super-Challenge” January 29, 2009. The New England Journal of Medicine. http://content.nejm.org/cgi/content/full/360/5/439...
View Full Document

This note was uploaded on 07/30/2009 for the course HEALTH SYS 1501 taught by Professor Sweeney during the Spring '09 term at Texas A&M.

Ask a homework question - tutors are online