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VertPhys25 - Lecture 25*Ganglion Cells Code Contrast...

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Lecture 25 *Ganglion Cells Code Contrast Summary: *Light always hyperpolarizes and dark always depolarizes *Bipolar cell’s transmitters to ganglion cells are always EXCITATORY *The transmitter from the rod to the bipolar cell can be either excitatory or inhibitory *Horizontal cells release either inhibitory or excitatory transmitters (opposite of rod- bipolar transmitter) * OffC-OnS-excitatory transmitter, inhibitory horizontal *OnC-OffS- inhibitory transmitter, excitatory horizontal Off Center On Surround: Transmitter from rod EXCITES bipolar cell, horizontal transmitter INHIBIT bipolar cell Dark: 1) Rod is depolarized , releases transmitter on bipolar cell 2) Transmitter depolarizes bipolar cell, releases transmitter on ganglion cell 3) ganglion cell fires AP Dark: With Horizontal Cell (only activated in surround) Rod is depolarized , releases transmitter onto horizontal cell, which is then depolarized and releases inhibitory transmitter on the bipolar cell; bipolar cell releases less transmitter
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