Lecture 25--Retina_II

Lecture 25--Retina_II - -30 mV-70 mV Stephen Kuffler...

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-30 mV -70 mV
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Stephen Kuffler
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Ganglion cell fires when light is on Ganglion cell fires when light goes off Ganglion cell fires when light goes off Ganglion cell fires when light goes off No response + - - - - Receptive field of ganglion cell Place microelectrode in optic nerve to record action potentials from retinal ganglion cells Flash a spot of light On the screen
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++ + O n C en te r - ff Su rr ou nd of f ar on a f area on area l l l l Off response Off response l l Off response l l l
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Ganglion cells code contrast Contrast – the difference in brightness between the center and the surround
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Off center--On surround Dark 1) Rod is depolarized, releases transmitter on bipolar cell. 2) Transmitter depolarizes bipolar cell, releases transmitter on ganglion cell. 3) Ganglion cell fires APs.
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Off center--On surround Dark 1) Rod is depolarized, releases transmitter on bipolar cell. 1) Transmitter depolarizes bipolar cell, releases transmitter on ganglion cell. 1) Ganglion cell fires APs. 1) Rod is depolarized, releases transmitter on horizontal cell. 1) Transmitter depolarizes horizontal cell, releases inhibitory transmitter on bipolar cell. 3) Bipolar cell releases less transmitter on ganglion cell . 4) Ganglion cell fires fewerAPs. Dark Without horizontal cell With horizontal cell
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Off center--On surround Light 1) Rod is hyperpolarized, releases less transmitter on bipolar cell.
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This note was uploaded on 07/31/2009 for the course BIO 365R taught by Professor Draper during the Spring '08 term at University of Texas.

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Lecture 25--Retina_II - -30 mV-70 mV Stephen Kuffler...

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