Playing MapMan Help - Playing with MapMan a user-driven...

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Playing with M a p M a n … a user-driven tool to display genomics data sets onto diagrams of metabolic pathways and other biological processes… Max Planck Institute of Molecular Plant Physiology
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Max Planck Institute of Molecular Plant Physiology A problem of multiparallel data Lists : difficult decisions to sort tabular data according to extend of change or to use sorting based on labels and descriptions. Figures : density of data points in scatterplots does not allow an easy identification of genes with similar function.
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Max Planck Institute of Molecular Plant Physiology One possible solution Organize similar data points and group them together for a graphical output: „one picture tells more than a thousand words“
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Max Planck Institute of Molecular Plant Physiology Concept MapMan groups items (genes, enzyme activities, metabolite) into functional pathways „BINS“ Rubisco Light harvesting complex Aldolase Phosphoglucomutase Phosphoglucoisomerase Triose Phosphate Isomerase
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Max Planck Institute of Molecular Plant Physiology Structuring The BIN Items are displayed together as color-coded squares 5 genes in group B 6 genes in group A
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Max Planck Institute of Molecular Plant Physiology Structuring The color-coded squares are painted on a picture representing the biological background Glucose-6-Phosphate Fructose-6-Phosphate Fructose-2,6-Bis-Phosphate A small part of a pathway
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Max Planck Institute of Molecular Plant Physiology
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This note was uploaded on 08/01/2009 for the course HORT hor-11-12 taught by Professor Park during the Spring '09 term at A.T. Still University.

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Playing MapMan Help - Playing with MapMan a user-driven...

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