5 - PROKARYOTIC DIVERSITY BIOL 4125 SPRING 2009 LECTURE 5...

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PROKARYOTIC DIVERSITY BIOL 4125 SPRING 2009 LECTURE 5 Bioenergetics: Unity in diversity
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Albert Jan Kluyver Professor of Microbiology in Delft (1920-1956) • Thought microbial taxonomy should be based on a combination of morphology and physiology, rather than simply on morphological features. • Believed there would be an energy shortage in the future and talked of the biological production of fuel alcohol. • Responsible for the "Unity in Diversity" description of biochemistry. • Recognized the underlying chemical unity of all living organisms: “From elephant to butyric acid bacterium – it is all the same!“ • One of his first Ph.D. students was Cornelius van Niel, one of the scientists responsible for taking the Delft School of Microbiology to the USA. http://www.bt.tudelft.nl 1888–1956
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“Die Einheit in der Biochemie” Kluyver and Donker (1926) Chem. Zelle Geweke. 13:134-190 • Albert Jan Kluyver and Hendrick Jean Louis Donker propose a universal model for aerobic and anaerobic metabolic events in cells based on the transfer of hydrogen atoms . • The “unity theory of biochemistry” states that all basic enzymatic reactions which support and maintain life processes within cells of organisms have more similarities than differences. • This concept of biochemical unity stimulates many investigators to use bacteria as model systems for studying related eukaryotic, plant and animal biochemical reactions that are essentially identical at the molecular level.
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5 - PROKARYOTIC DIVERSITY BIOL 4125 SPRING 2009 LECTURE 5...

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