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Unformatted text preview: 1/2/2008 1 Todays Outline Introduction 8 January 2008 Russell L. Malmberg 1 Grades Topic Overview What is Bioinformatics? The definition of bioinformatics is not universally agreed upon. Generally speaking, we define it as the creation and development of advanced information and computational technologies for problems in biology, usually molecular biology. As such, it deals with methods for storing, retrieving and analyzing biological data, such as nucleic acid (DNA/RNA) and protein sequences, structures, functions, pathways and interactions. Some people construe bioinformatics more narrowly, and include only those issues dealing with the management of genome project sequencing data. Others construe bioinformatics more broadly and include all areas of computational biology, including population modeling and numerical simulations. Quotation from Doug Brutlag Course Objectives Applications and concepts of computational technologies for solving problems in molecular genetics. Current applications and their underlying computational BIOL/PBIO 4550/6550 Bioinformatics Applications 8 January 2008 Russell L. Malmberg 3 Current applications and their underlying computational algorithms will be discussed. Topics include: sequence and structure databases; sequencing; mapping; sequence alignments (dynamic programming); motifs and profiles; phylogeny reconstruction; probabilistic approaches (Markov models). Course Web Pages http://www.plantbio.uga.edu/courses/bioinformatics/index.html Course Materials Page: 8 January 2008 Russell L. Malmberg 4 user name = bioinformatics password = isablast (case sensitive) RCC Accounts, Grades Computers: No computers are provided, except during lab sessions. You will be able to get accounts on RCC for access to many of the sequence analysis 8 January 2008 Russell L. Malmberg 5 access to many of the sequence analysis programs. Grading: Periodic assignments collected by web submission. Transmission of a virus or worm will have a negative effect on your grade. Grading Two take-home problem sets, 100 points each 1. Before the mid-point of the semester 2. At the end of the semester Periodic Homework Lab Reports 2 point scale 8 January 2008 Russell L. Malmberg 6 Periodic Homework Lab Reports, 2 point scale. 2 points = mostly right 1 point = missed something major Graduate Students taking 6550: Database Report, 25 points 1/2/2008 2 Academic Honesty All academic work must meet the standards contained in "A Culture of Honesty"....
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This note was uploaded on 08/04/2009 for the course PLANT BIOL PBIO6550 taught by Professor Russellmalmberg during the Spring '08 term at University of Georgia Athens.
- Spring '08