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Unformatted text preview: FINAL EXAM, Biochemistry 102/2007 I. (25 points) Fill in all of the enzyme catalyzed reactions which convert the substrate on the left to the product
on the right. Draw the correct structure for each intermediate molecule. Include the names or abbreviations
of any other reactants and products (e. g., ATP, ADP, P,, NAD+, NADH, etc. ), and any required prosthetic \
groups (e. g. TPP, FAD, biotin, etc. ). Identify the reaction catalyzed by acetyl CoA carboxylase. O
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maecuzc ,3 AC? ,- O "'0 anti-SAC"? ‘ ’ 1 CH3CH2CH2C(O)—SACP w (B) Name the coenzyme from which the prosthetic group of acyl carrier protein is derived. Describe the
essential role of this prosthetic group with the aid of a diagram of the fatty acid synthase complex. . """‘"\ 2 II. (45 points) Fill in all enzyme catalyzed reactions needed to convert the substrate on the left to the product
on the right. Draw the correct structure for each intermediate molecule. Include the names or abbreviations of any other reactants and products (e.g., ATP, ADP, Pi, NAD+, NADH, etc.), and any required prosthetic groups
(e.g., TPP, FAD, biotin, etc.). ' ' (A) Pyruvate (gluconeogenesis in liver) (Indicate which steps occur in the matrix and which \ occur in ihe cytosol.)l pinm. y.
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III. Moints) In the space below please draw all of the enzymatic reactions needed to convert the amino
nitrogen of alanine to a nitrogen of urea. Assume that your starting materials are alanine, OL-ketoglutarate,
aspartate, arginine, and bicarbonate. Draw the correct structure for each intermediate molecule (if you don’t
know the structure, give the correct name to receive partial credit). Include the names or abbreviations of
any other reactants and products (e.g., ATP, ADP, Pi, NAD+, FAD, ADH, etc.), any required cofactors (e.g.,
biotin, TPP,,. ) ’,./‘"*~~, "\ ' i y “T I .flé‘rf‘s‘ COLE." ' , p\\ , 5 . IV. ,MJpoints) Answer one of the following two problems. Please cross out the one that you don't wish to have graded. A. Outline the steps starting with a decrease in blood glucose on the left and ending with the relevan_t changes
in the activities of glycogenolysis and gluconeogenesis' 1n the liver on the right. Use arrows ( T or J. ) to show the effect on messenger molecule concentration, enzyme activity, and pathway activity at each step, as
in the lecture handout “Responses 1n liver cells when blood glucose levels are low” 1.325;. =% t if; fFei/mfl: .f
{/43 Win; fl\ ‘17 (F218;?) B. Give a simple diagram \thet shows the inter relationship between photosynthesis and respiration (the lecture
handout ‘The electron cycle of life” will receive full credit). o , a‘. ...
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- Spring '08
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- Biochemistry, Enzyme, Acetyl CoA carboxylase, correct structure, required prosthetic groups, intermediate molecule
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