{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

sp09 midterm exam notes wks4-5

sp09 midterm exam notes wks4-5 - BIOCHEMISTRY 102 MIDTERM...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
BIOCHEMISTRY 102 MIDTERM EXAM NOTES FOR WEEKS 4 & 5 April 30, 2009 The midterm exam will cover the material presented in the first 5 weeks of lecture and in problem sets 1 through 5. The midterm exam notes below give you a specific description of the major areas that will be covered in this exam from lectures in weeks 4 & 5 and from problem sets 4 & 5. A thorough understanding of the material in this handout should prepare you for exam questions from weeks 4 & 5. Copies of the exams from past years can be obtained at the course website. ( Note: the second midterm in 2007 and 2008 has problems from the material in weeks 4& 5). Note: No examination question will deal with information presented in the text but not in lecture, midterm exam notes, or a problem set. 1 . Some problems from problem sets #4 & 5, or slight variations on these problems, will be on the exam. 2 . Know the sequence of reactions, the structure and name of each molecule, and the use of ATP, NAD + , NADH, FAD, FMN, biotin, TPP, etc., or their equivalents, for the following pathways. You need not memorize the reaction mechanisms or the structure of enzyme bound intermediates, except as noted below. You also need not memorize the name of each enzyme, but you should be able to identify the reaction if given the name of the enzyme. (a) Citric acid cycle + pyruvate dehydrogenase (handout 11) . (b) The conversion of pyruvate to oxaloacetate by pyruvate carboxylase. (c) Glycerol phosphate shuttle (glycerol P dehydrogenase in the cytosol uses cytosolic NADH to reduce dihydroxyacetone phosphate to glycerol P; glycerol P then diffuses to a different glycerol P dehydrogenase which is in the outer face of the inner mitochondrial membrane and contains an FAD prosthetic group. The mitochondrial glycerol P dehydrogenase oxidizes glycerol P back to dihydroxyacetone phosphate with the formation of FADH 2 , and then passes the electron pair from FADH 2 to UQ in the inner membrane. Since Complex I is bypassed, only 1.5 ATPs are made per cytosolic NADH.) ( handout 21 ) (d) Electron Transport. You should know the role of complexes I, II, III, and IV in electron transport and the prosthetic groups of each (i.e., Complex I: FMN and FeS; Complex II: FAD and FeS; Complex III: 2 cytochrome b, FeS, and cytochrome c 1 ; and Complex IV: cytochromes a and a 3 , copper atoms CuA and CuB).
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}