Cell_Signaling_Guide - 8. Define the term second messenger....

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Lecture Objectives - Cell Signaling 1. List and briefly define the three stages of cell signaling. 2. Describe the nature of a ligand-receptor interaction and state how such interactions initiate a signal-transduction system. 3. State where signal receptors may be located in target cells. 4. Compare and contrast G-protein-linked receptors and tyrosine-kinase receptors. 5. Describe two advantages of using a multistep pathway in the transduction stage of cell signaling. 6. Describe how phosphorylation propagates signal information. 7. Explain how protein phosphatases turn off signal-transduction pathways.
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Unformatted text preview: 8. Define the term second messenger. Briefly describe the role of these molecules in signaling pathways. 9. Describe how cyclic AMP is formed and how it propagates signal information in target cells. 10. Describe how signal amplification is accomplished in target cells. Key Words adenylyl cyclase cyclic AMP (cAMP) G protein G-protein-linked receptor ligand protein kinase protein phosphatase reception receptor tyrosine kinase response second messenger signal transduction pathway transduction...
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This note was uploaded on 08/05/2009 for the course BILD 1 taught by Professor Boulanger during the Fall '08 term at UCSD.

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