Lect4B_07_Obj&WordList - 8 Describe the mechanisms...

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Lecture 4B - Thermodynamics, Kinetics, and Enzymes Lecture Objectives 1. Write and define each component of the equation for free-energy change. 2. Distinguish between exergonic and endergonic reactions in terms of free energy change. 3. Describe the structure of ATP and identify the major class of macromolecules to which ATP belongs. 4. Explain how ATP performs cellular work. 5. Explain why an investment of activation energy is necessary to initiate a spontaneous reaction. 6. Describe how thermodynamic and kinetic considerations each influence reactions in biological systems. 7. Explain how enzyme structure determines enzyme specificity.
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Unformatted text preview: 8. Describe the mechanisms by which enzymes lower activation energy. 9. Distinguish between competitive inhibition and noncompetitive inhibition.* 10. Discuss how feedback inhibition and allostery contribute to biological regulation.* *[Not on Midterm] Word List activation energy active site allosteric regulation* ATP (adenosine triphosphate) catalyst competitive inhibitor* coupled reactions endergonic reaction energy energy coupling enthalpy entropy enzyme-substrate complex equilibrium constant (Keq) exergonic reaction feedback inhibition* free energy glutamate glutamine noncompetitive inhibitor* substrate...
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