Lab 01 - Endocrine Anatomy and Histology.docx - Nur 0003 Lab 01 Endocrine Anatomy and Histology Goals 1 To Identify the location of the major endocrine

Lab 01 - Endocrine Anatomy and Histology.docx - Nur 0003...

This preview shows page 1 - 3 out of 12 pages.

Nur 0003 Lab 01 - Endocrine Anatomy and Histology Goals 1. To Identify the location of the major endocrine glands in the body. 2. To understand the histology of the major endocrine glands. 3. To learn the major hormones secreted by the major endocrine glands. I. The Endocrine System A. Location of major endocrine glands 1. Head Hypothalamus(junction between the endocrine and nervous systems) Pituitary (a.k.a. hypophysis) Pineal body 2. Neck Thyroid Parathyroid – posterior of thyroid gland 3. Thorax Thymus(especially enlarged in fetuses and infants) Heart 4 Abdomen Pancreas Adrenals Gonads - ovaries and testes Stomach and intestinal linings B. Hormones and their Targets 1. Hormone Chemical Signal Released in small amounts by specialized epithelial cells Travels through blood to target tissues. 2. Targets Target tissues have receptors that will bind with the appropriate hormone. Receptors can be membrane bound (protein) or intracellular (steroid) Some target tissues will down regulate over time, meaning they become less sensitive to the amounts of hormone present. 1
Image of page 1
Nur 0003 II. Pituitary Gland A. Anatomy of the Pituitary gland Located in the sella turcica (Turkish saddle) of the sphenoid bone. Connected to the hypothalamus by a stalk called the infundibulum. Adenohypophysis (anterior pituitary) - cuboidal epithelial tissue. The anterior pituitary is connected the hypothalamus via a portal system (a special system of blood vessels in which two capillary beds are connected together directly) known as the hypothalamohypophyseal portal system . Releasing hormones from the hypothalamus trigger the anterior Pituitary to secrete its hormones, or in some special cases inhibit the anterior pituitary from releasing hormones(the inhibiting hormones) Examples of releasing and inhibiting hormones include: GHRH, GnRH, TRH, CRH, and PIH and GHIH. Neurohypophysis (posterior pituitary) - nervous tissue. The posterior pituitary does not secrete* any hormones because it is primarily nervous tissue. Axons from the hypothalamus pass down the hypothalamohypophyseal tract to terminate here and release their chemical products as needed. B. Hormones secreted by the anterior pituitary gland 1. Growth Hormone (GH) a.k.a. somatotropin Structure- protein Target – Many tissues, but mainly muscle and connective tissue. Response - a.a uptake for protein & glycogen synthesis, growth in tissues, stimulates muscle and bone growth. Clinical - pituitary dwarfism and pituitary giants (gigantism), and acromegaly 2. Prolactin (PRL) Structure – protein Target - mammary glands (primarily) Response - stimulates mammary glands to produce milk soon after birth Tropic hormones - hormones whose targets are other endocrine glands.
Image of page 2
Image of page 3

You've reached the end of your free preview.

Want to read all 12 pages?

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture