World of Chem: Drugs – Midterm 1
Lecture 1&2
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1.
A.S.A
decreases inflammation but
acetaminophen
does not
2.
Taking a fraction of an
A.S.A
tablet a day has been shown to be beneficial in the
prevention of heart attacks
3.
Acetaminophen
can be a problem in that liver damage can take place if it is taken
after drinking on an empty stomach
4.
Anacin
contains caffeine in addition to A.S.A
5.
Homeopathic drugs are prepared by successive dilutions; one positive aspect of
homeopathic preparations is that they are normally safe
6.
Thalidomide
is effective in the treatment of leprosy
7.
Ingestion of 1 microgram of
botulin
toxin would be extremely harmful to a person
8.
The most prescriptions in Canada are written for pain (Tylenol with codeine) and
Ulcers
9.
Balloon angioplasty for esophagus enlargement usually involves mild sedation
10. Guinea worm disease has been significantly reduced by filtering the drinking water to
remove worm-carrying fleas
11.
Aspirin
is a synthetic derivative of a salicylic acid, can be marketed in Canada by any
company and was introduced in the US at about the same time as heroin
12.
Acetaminophen
does not irritate the stomach
13.
Aspirin
shuts of the production of prostaglandins which are responsible for the
sensation of pain in that they stimulate nerve endings
14. The FDA has a series of priorities that it uses to judge a new drug which include
whether it is a new chemical entity, a new formulation for an old drug (like a patch)
or a new combination of two drugs not marketed this way before
15. Some antibiotics tie up to cytochrome 450 causing
Seldane
to build up causing heart
irregularities
16. The patent medicine era was approximately from 1850 to the early 1990s
17.
Quinine
is found mainly in the bark of the cinchona tree
18. Smallpox is considered to be eradicated in the world today
19. Jokob Bohme was largely responsible for the Doctrine of Signatures involving a
relationship between a creation of God and its purpose – such as walnuts for the brain
and bloodroot for curing blood diseases
20. It is possible for a company to see the same drug both under a brand name and a
generic name at very different prices; the same drug can be sold at very different
prices in different countries
21. Blocked coronary arteries have been open with balloon and laser angioplasty
22.
Aspirin
(A.S.A) interferes with the production of prostaglandins responsible for the
production of acid in the stomach
23. Reye Syndrome is thought to be triggered by taking aspirin. This applies to young
people only
24. The placebo effect concerns at least 30% of the participants in a study
25. The Doctrine of Signatures is the association of a disease and a plant of some kind
26.
Vioxx
blocks the COX-2 receptor sites associated with pain, while leaving the COX-
1 sites which are associated with stomach protection, unaffected
27. Life expectancy for a newborn male at the turn of the 1900s was about 47 years
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World of Chem: Drugs – Midterm 1
28. Merck recently took
Vioxx
(arthritis) off the market for unfavorable side-effects

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- Spring '09
- y
- Genetics, patent medicine era
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