lecture 5

lecture 5 - Lecture 4: Multiple Gene Inheritance I...

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BIOL 202 - T. Western 20051 Lecture 4: Multiple Gene Inheritance I Mendel’s law of independent assortment. Working with independent assortment. Chromsomal basis of independent assortment. **Problem Set 2 is NOW AVAILABLE on-line** Reading (9th edition) pp.  89-102. (8th edition) pp. 36-42
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Why bother with the Chi Square Test? ….because drawing gametes from a heterozygote is like rolling dice or drawing cards from a deck….chance plays a role in the outcome.
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Example: Is flower colour controlled by one gene that exhibits partial dominance? Red WW White ww Pink Ww F1 : Parents (P) : F2: 65 140 45 Total = 250
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Is the Null hypothesis supported by the data? Calculate the Chi-square: Hypothesis: 1:2:1 65 140 45 (Observed - Expected) 2 Expected Chi Square = Σ
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Histogram of Chi-square values In other words, only 5% of the time will the Chi-square value exceed 5.99 How large a Chi-square value must be obtained before we decid to reject the hypothesis? Let’s conduct the cross thousands of times and each time calculate Chi-square Our calculated Chi Square value exceed the critical value of 5.99,
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BIOL 202 - T. Western 20056 Chi-square test: Critical values depend on the number of degrees of freedom (df) in the test
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BIOL 202 - T. Western 20057
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lecture 5 - Lecture 4: Multiple Gene Inheritance I...

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