lecture 6

lecture 6 - Lecture 5: Multiple Gene Inheritance II...

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BIOL 202 - T. Western 20051 Lecture 5: Multiple Gene Inheritance II Independent assortment and recombination Polygenic inheritance. Organelle genes (Cytoplasmic inheritance) **Problem Set 1 and 2 are NOW AVAILABLE on-line** Reading (9th edition) pp.  102-118 (8th edition) pp. 96-107;  55-59; 644-647
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BIOL 202 - T. Western 20052 Figure 3-18 Cell showing nucleoids within mitochondria Organelle genes (Cytoplasmic inheritance)
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BIOL 202 - T. Western 20053 Pedigree of a mitochondrial disease Organelle genes (Cytoplasmic inheritance)
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BIOL 202 - T. Western 20054 Model for cytoplasmic segregation Organelle genes (Cytoplasmic inheritance)
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BIOL 202 - T. Western 20055 Figure 3-21 Variegated leaves caused by a mutation in cpDNA Organelle genes (Cytoplasmic inheritance) Can there be segregation of cytoplasmically inherited genes? Yes. ...but not the meiotic type.
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BIOL 202 - T. Western 20056 A mother heteroplasmic for a mitochondrial disease phenotype has identical (monozygotic) twins. Which of the following results would you expect? (assume the heteroplasmy is associated with a mitochondrial DNA disease phenotype and is solely determined by a mutation in a single mitochondrial gene) a) The disease phenotype may manifest in one twin yet not in the other. b) Both twins are certain to express (present) the disease phenotype and to
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lecture 6 - Lecture 5: Multiple Gene Inheritance II...

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