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Unformatted text preview: BlOL 300 VERSION # 1 Facultv of Science FINAL EXAMINATION BIOLOGY-300 MOLECULAR BIOLOGY OF THE GENE VERSION # 1 Examiner: Prof. P. Holland Associate Examiner: Prof. R. Dunn Thursday, December dh, 2005 2 P.M. -5 P.M. Including the cover page, this exam comprises 13 pages. All questions are multiple choice: There are 50 multiple choice questions worth 2 points each. These questions are to be answered using the first 50 places on the SHORT (120 response or less) SCANTRON sheet provided. You should answer all 50 questions. Be sure to fill in the STUDENT NUMBER BOX on the left side of the SCANTRON sheet as well as the VERSION BOX to the immediate right of the student box, indicating which version number of the exam you used. WARNING: The Examination Security Monitor Program detects pairs of students with unusually similar answer patterns on multiple choice exams. Data generated by this program can be used as admissible evidence, either to initiate or corroborate an investigation or a charge of cheating under Section 16 of the Code of Student Conduct and Disciplinary Procedures. Each student is responsible for checking that hislher question set contains the correct number of pages and questions. Calculators are NOT required or permitted. No notes or texts are allowed You may keep the exam but be sure to turn in your completed SCANTRON sheet. Px&m 13 p R / / 7 ~ t ~ JW~M- s / L ) a 1. Which of the following components of the interferon+ enhanceosome has histone acetyltransferase activity? A) NF-KB B) IRF3 C) c-Jun D) p300/CBP E) None of the above 2. This receptor is activated exclusively at the posterior and anterior terminal regions of the embryo. Which is it? A) Toll B) Cactus C) Torso D> Spatzle E) Nanos 3. Which of the following statements regarding HMGl is not correct? A) It binds to PRDIV of the interferon p enhanceosome. B) It binds in the major groove of DNA. C) It binds to AT-rich sites D) It is a highly basic protein E) It binds cooperatively with NF-KB. 4. During early development, the Drosophila embryo forms a syncytial blastoderm. Which of these statements best describes this stage of development. A) A tube of cells with mesoderm on the ventral side. B) A hollow tube with a single layer of nuclei at the periphery. C> A tube of cells with mesoderm on the dorsal side. D) A hollow tube with a single layer of cells at the periphery E) A tube with 4 nuclei localized to the anterior- dorsal region 5. Activation of the twist gene is critical to dorsal- ventral patterning in the Drosphila embryo. Twist acts with Dorsal to turn on what important gene? A) Twist itself B) Dorsal C) Decapentaplegic D) Hunchback E) Snail 6. Which of the following statements regarding the SV40 enhancer is not correct?...
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