Bio2 Lecture 18

Bio2 Lecture 18 - Bio2 Lecture 18 3/29/05 Review for Exam...

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Bio2 Lecture 18 3/29/05 Review for Exam II April 3 (Sunday) 2-4 pm Hickman 138 First 30 min: Dr. Katz Middle 30 min: Excretion Lecture Last 60 min: mock exam 20 questions Bring bio questions Test up until this lecture Immune Response (Complex and Sophisticated) 2 different types of immunity - Nonspecific – acts right away, virus, or foreign object being attacked immediately, the macrophages, phagocytes - Neutrophils, and dilation also causes wbc’s to come to this area - This causes redness, swelling, heat (heat kills bacteria and helps wbc react faster by increasing?!) - Enzyme in wbcs cause pain when they die - Specific immunity – skin, natural killer cells can work both specific and non specific - Natural killer cells that attack cancerous cells Immune response is specific 1. Cell-mediated – don’t have antibodies 2. Antibody- mediated B cells produce antibodies, and some b cells called memory cells, remember what antibodies kill a certain virus Players Cells involved in the immune response - Lymphocytes o B – lymphocytes – specific, antibody mediated, b for bone, produced in bone marrow, mature in bone marrow and then go into system o T – lymphocytes – cell mediated, produced in bone marrow, but mature in thymus, specific o Natural killer (NK) cells – both specific and non-specific, cell mediated - Phagocytes – these are cells that go straight after the virus or bacterium - Bone marrow produces many types of cells o White blood cells o Monocytes – develop into macrophages, special type is dendritic cell o Natural killer cells o Those that go to thymus to mature (T cells)\
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o B cells and these mature in bone marrow - Anti-body mediated immunity o Bacterium enters into body, and on its body are antigenic determinants o Signals macrophage to come and get this bacterium, that is being signaled by antibodies that attach to it o Macrophage then engulfs it (Phagocytosis) o It takes antigenic determinants and puts it on the outside of itself after the bacterium is devoured - Antibodies (immunoglobulins) o Large protein molecules o Produced by B cells o At any one time we can produce a million different antibodies
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This note was uploaded on 08/10/2009 for the course BIO 102 taught by Professor Brey during the Spring '08 term at Rutgers.

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Bio2 Lecture 18 - Bio2 Lecture 18 3/29/05 Review for Exam...

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