Cellular Neuroscience Test 2

Cellular Neuroscience Test 2 - Cellular Neuroscience Test 2...

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Cellular Neuroscience Test 2 (Midterm) 1. The basis of neuronal excitability is the rapid displacement of ________ through the lipid bilayer: electrically charged ions 2. The most abundant cations in a physiologic solution usually are: Na ions 3. Ion channels are composed of: one or more protein subunits 4. Ion channels are permeable: to one or more specific ion type (s) 5. Ionic “pumps” are: proteins bringing particular ion species across the membrane 6. The difference between an ion pumps (P) and an ion channels (C) is that: P actively move ions against their gradient while C do not, P create ion concentration gradients while C do not, C allow to diffuse down the concentration gradients, P use ATP or other forms of energy to move ions against their concentration gradient (ALL OF THE ABOVE) 7. In a physiologic situation the “Na-K pump”: brings 2 K into the cell and 3 Na outside the cell 8. The difference between an “ATPase” and an “exchanger” pump is: an ATPase always uses ATP energy while an exchanger does not 9. Ohm’s law can be written as current I=conductance *voltage (I= gV). What does that mean? That the current flowing between two points is proportional to the voltage difference between these two points, and g is the proportionality constant 10. the functional difference between “leak” channels (L) and “gated” (G) channels is: G are opened by specific stimuli, L are always open 11. in a “voltage-gated” channel the single channel open probability depends mainly on: the transmembrane voltage 12. in a membrane “ligand-gated” channel, the single-channel open-probability depends mainly on: the concentration of a ligand in the extracellular side of
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Cellular Neuroscience Test 2 - Cellular Neuroscience Test 2...

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