Note: The below given guide is to help you focus on the topics that you need to be thorough. Be aware that it cannot be used solely for the exam preparation. It cannot replace lecture notes, and text book on the topics discussed in the class. . Chapter 12 o chemotherapy antimicrobial drugs synthetic drugs antibiotics, selective toxicity,spectrum of drugs, Broad and narrow range of a drug, superinfection and its causes o difference between semisynthetic, synthetic drugs and antibiotics o List and describe several actions of antimicrobial drugs: o Antibacterial drugs mechanisms: inhibitors of cell wall synthesis, inhibition of enzymatic activity o Penicillins, cephalosporins, becitracin, isoniazid, vancomycin, polymyxins, gluroquinolones, rifamycin, aminoglycosides, chloramphenicol, macrolids, tetracyclins, sulfaonamindes o injury to plasma membrane, nucleic acid synthesis inhibition, protein synthesis and biostatic agents such as sulfa drugs
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