A well established clinical application of adult stem

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Unformatted text preview: ich plays an important role in the treatment of a variety of cancers. As discussed in Chapter 18, most cancers are treated by chemotherapy with drugs that kill rapidly dividing cells by damaging DNA or inhibiting DNA replication. These drugs do not act selectively against cancer cells but are also This material cannot be copied, reproduced, manufactured, or disseminated in any form without express written permission from the publisher. © 2009 Sinauer Associates, Inc. UNCORRECTED PAGE PROOFS 22 CHAPTER 17 FIGURE 17.22 Hematopoietic stem cell transplantation A cancer patient is treated with high doses of chemotherapy, which effectively kill tumor cells but normally would not be tolerated because of potentially lethal damage to the hematopoietic system. This damage is then repaired by transplantation of new hematopoietic stem cells. Stored umbilical cord blood from an unrelated donor can also be used as a source of hematopoietic stem cells for transplantation. High dose chemotherapy Hematopoietic stem cell transplant Tumor Cancer patient Drugs kill tumor cells Toxicity to hematopoietic system Restor...
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This note was uploaded on 08/25/2009 for the course BIO 315 taught by Professor Steiner during the Spring '08 term at Kentucky.

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