This preview shows page 1. Sign up to view the full content.
Unformatted text preview: ich
plays an important role in the treatment of a variety of cancers. As discussed in Chapter 18, most cancers are treated by chemotherapy with drugs
that kill rapidly dividing cells by damaging DNA or inhibiting DNA replication. These drugs do not act selectively against cancer cells but are also
This material cannot be copied, reproduced, manufactured, or disseminated in any
form without express written permission from the publisher.
© 2009 Sinauer Associates, Inc. UNCORRECTED PAGE PROOFS
22 CHAPTER 17 FIGURE 17.22 Hematopoietic
stem cell transplantation A cancer
patient is treated with high doses of
chemotherapy, which effectively kill
tumor cells but normally would not be
tolerated because of potentially lethal
damage to the hematopoietic system.
This damage is then repaired by transplantation of new hematopoietic stem
cells. Stored umbilical cord blood
from an unrelated donor can also
be used as a source of hematopoietic stem cells for transplantation. High dose
stem cell transplant Tumor
Cancer patient Drugs kill tumor cells
Toxicity to hematopoietic system Restor...
View Full Document