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although the precise roles of these factors in regulating different types of
stem cells within their distinct niches remains to be understood. Medical Applications of Adult Stem Cells
The ability of adult stem cells to repair damaged tissue clearly suggests their
potential utility in clinical medicine. If these stem cells could be isolated and
propagated in culture, they could in principal be used to replace damaged
tissue and treat a variety of disorders, such as diabetes or degenerative diseases like muscular dystrophy, Parkinson’s or Alzheimer’s disease. In some
cases, the use of stem cells derived from adult tissues may be the optimal
approach for such stem cell therapies, although the use of embryonic stem
cells (discussed in the next section of this chapter) is likely to provide a more
versatile approach to treatment of a wider variety of disorders.
A well-established clinical application of adult stem cells is hematopoietic stem cell transplantation (or bone marrow transplantation), wh...
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