In addition signaling by the tgf b hedgehog and notch

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Unformatted text preview: tion, although the precise roles of these factors in regulating different types of stem cells within their distinct niches remains to be understood. Medical Applications of Adult Stem Cells The ability of adult stem cells to repair damaged tissue clearly suggests their potential utility in clinical medicine. If these stem cells could be isolated and propagated in culture, they could in principal be used to replace damaged tissue and treat a variety of disorders, such as diabetes or degenerative diseases like muscular dystrophy, Parkinson’s or Alzheimer’s disease. In some cases, the use of stem cells derived from adult tissues may be the optimal approach for such stem cell therapies, although the use of embryonic stem cells (discussed in the next section of this chapter) is likely to provide a more versatile approach to treatment of a wider variety of disorders. A well-established clinical application of adult stem cells is hematopoietic stem cell transplantation (or bone marrow transplantation), wh...
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This note was uploaded on 08/25/2009 for the course BIO 315 taught by Professor Steiner during the Spring '08 term at Kentucky.

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