Cooper5e_Ch17

Interest in these cells reached a new peak of

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Unformatted text preview: Embryo FIGURE 17.23 Culture of mammalian embryonic stem cells (A) Embryonic stem cells are cultured from the inner cell mass of an early embryo (blastocyst). (B) Scanning electron micrograph of cultured embryonic stem cells. (Yorgos Nikas/Photo Researchers, Inc.) Culture of embryonic stem cells (B) Inner cell mass This material cannot be copied, reproduced, manufactured, or disseminated in any form without express written permission from the publisher. © 2009 Sinauer Associates, Inc. UNCORRECTED PAGE PROOFS CELL DEATH AND CELL RENEWAL Undifferentiated ES cells maintained in LIF Removal of LIF FIGURE 17.24 Differentiation of embryonic stem cells Mouse embryonic stem (ES) cells are maintained in the undifferentiated state in the presence of LIF. If LIF is removed from the culture medium, the cells aggregate to form embryoid bodies and then differentiate into a variety of cell types. Embryoid bodies Cell differentiation Blood cells Epithelial cells Adipocytes Smooth muscle cells Nerve cells from human embryos, raising the possibility...
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