It may thus be possible to derive populations of

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Unformatted text preview: ave been developed to direct the differentiation of both mouse and human embryonic stem cells into cardiomyocytes, which have been used to repair heart damage resulting from myocardial infarction in mice. Likewise, considerable progress has been made in directing the differentiation of embryonic stem cells to neurons, which have been used for transplantation therapy in rodent models of Parkinson’s disease and spinal cord injury, and to insulin-producing pancreatic cells, which have been used for therapy in mouse models of diabetes. A great deal of current research is therefore focused on the development of culture conditions to promote the differentiation of embryonic stem cells along specific pathways, thereby producing populations of differentiated cells that can be used for transplantation therapy of a variety of diseases. This material cannot be copied, reproduced, manufactured, or disseminated in any form without express written permission from the publisher. © 2009 Sinauer Associates, Inc. 25 Heart muscle cells UNCORRECTED PAGE PROOFS 26 CHAPTER 17 (A) (B) Unfertilized egg Adult somatic cell Remove egg chromosomes...
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This note was uploaded on 08/25/2009 for the course BIO 315 taught by Professor Steiner during the Spring '08 term at Kentucky.

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