Cooper5e_Ch17

The endothelial cells that line blood vessels figure

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Unformatted text preview: entiated cell that remains capable of proliferation. Proliferation of endothelial cells allows them to form new blood vessels as needed for repair and regrowth of damaged tissue. Endothelial cell proliferation and the resulting formation of blood capillaries is triggered by a growth factor (vascular endothelial growth factor or VEGF) produced by This material cannot be copied, reproduced, manufactured, or disseminated in any form without express written permission from the publisher. © 2009 Sinauer Associates, Inc. UNCORRECTED PAGE PROOFS CELL DEATH AND CELL RENEWAL 15 FIGURE 17.14 Endothelial cells Electron micrograph of a capillary. The capillary is lined by a single endothelial cell surrounded by a thin basal lamina. (© Dr. Don W. Fawcett/Visuals Unlimited.) Capillary lumen Endothelial cell cells of the tissue that the new capillaries will invade. The production of VEGF is in turn triggered by a lack of oxygen, so the result is a regulatory system in which tissues that have a low oxygen supply resulting from insufficient circulation stimulate endothelial cell proliferation and recruit new capillaries (Figure 17.15). Smooth muscle cells, which form the walls of larger blood vessels (e.g., arteries) as well...
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This note was uploaded on 08/25/2009 for the course BIO 315 taught by Professor Steiner during the Spring '08 term at Kentucky.

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