They can be readily grown in the undifferentiated

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Unformatted text preview: stem cells for many clinical applications. embryonic stem cell, pluripotency Somatic Cell Nuclear Transfer: Mammals have been cloned by somatic cell nuclear transfer in which the nucleus of an adult somatic cell is transplanted into an enucleated egg. This opens the possibility of therapeutic cloning in which embryonic stem cells would be derived from a cloned embryo and used for transplantation therapy of the donor of the adult nucleus. Although many obstacles need to be overcome, the possibility of therapeutic cloning holds great promise for the development of new treatments for a variety of devastating diseases. somatic cell nuclear transfer, therapeutic cloning, reproductive cloning Induced Pluripotent Stem Cells: Adult somatic cells can be converted to pluripotent stem cells in culture by four key transcription factors, potentially providing an alternative to embryonic stem cells for transplantation therapy. induced pluripotent stem cell This material cannot be copied, reproduced, manufactured, or disseminated in any form without express written permission from the publisher. © 2009 Sinauer Associates, Inc....
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This note was uploaded on 08/25/2009 for the course BIO 315 taught by Professor Steiner during the Spring '08 term at Kentucky.

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