Transgenics

Transgenics - What is transgenesis The study of phenotypic...

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What is transgenesis? The study of phenotypic responses in an organism that has been manipulated to contain a foreign piece of modified DNA, or transgene.
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Transgenic animal milestones First successful embryo transfer (1891) Zygote microinjection technology established (1966) Transgenic mouse production (1980) Transgenic domestic animals produced (1985) “Knockout” mouse production (1987; 1989) Nuclear transfer using adult cell nuclei in sheep (1997)
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Applications of transgenic animals odels in agricultural biomedical biotechnological Models in agricultural, biomedical, biotechnological, and veterinary fields. Genetic basis of diseases Gene therapy Disease resistance “Molecular farming” Enhancing production traits (growth, reproduction) Bioreactors enotransplantation Xenotransplantation
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rototype of a transgene Prototype of a transgene Gene Promoter Ubiquitous (expressed everywhere)
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This note was uploaded on 08/25/2009 for the course BIO 315 taught by Professor Steiner during the Spring '08 term at Kentucky.

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Transgenics - What is transgenesis The study of phenotypic...

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