Bme511_L1b_082709

Bme511_L1b_082709 - D A S ra P C P C P − ≤ ⎟ ⎟ ⎠ ⎞ ⎜ ⎜ ⎝ ⎛ − − = ≤ pl D A S ra D c C P C P C P C f Q Q max Cardiac Output

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Model of Circulatory System
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REGULATION OF CARDIAC OUTPUT Starling’s Law: ‘the output of the heart is equal to and determined by the amount of blood flowing into the heart, and may be increased or diminished within very wide limits according to the inflow” “Intrinsic control”
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“Extrinsic control”
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Mitral Valve Tricuspid Valve Aortic Valve Pulmonic Valve
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Aortic valve opens Aortic valve closes Mitral valve opens
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P pl P ra
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= pl D A S ra D C P C P C P C f Q Cardiac Output Curve V P - P pl Slope C D Slope C S ED ES
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Q c = 0 when Limitation on Q C : pl
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Unformatted text preview: D A S ra P C P C P − ≤ ⎟ ⎟ ⎠ ⎞ ⎜ ⎜ ⎝ ⎛ − − = ≤ pl D A S ra D c C P C P C P C f Q Q * max Cardiac Output Curve ⎟ ⎟ ⎠ ⎞ ⎜ ⎜ ⎝ ⎛ − − = pl D A S ra D C P C P C P C f Q Venous Return Curve A V A A V ra ms R C C C R R P P Q + + − = A V A A V ra ms R C C C R R P P Q + + − = V A V A ms C C V V P + + = Putting it all together…. . Glucose (x) Insulin (y) Normal Type-1 Diabetes β = 20% normal Type-2 Diabetes ν = 20% normal...
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This note was uploaded on 08/26/2009 for the course BME 511 taught by Professor Khoo during the Fall '08 term at USC.

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Bme511_L1b_082709 - D A S ra P C P C P − ≤ ⎟ ⎟ ⎠ ⎞ ⎜ ⎜ ⎝ ⎛ − − = ≤ pl D A S ra D c C P C P C P C f Q Q max Cardiac Output

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