Bme511_L1b_082709_final

Bme511_L1b_082709_final - Determination of steady state...

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Determination of steady state operating (equilibrium) point a c e f G f = e M f G L L = 0 L G f s a =
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L = L 0 -G M f e
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Depending on the relative slopes, the steady state equilibirum point could be stable or unstable L L (more about this later in the course…) f e f e
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Model of Circulatory System
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REGULATION OF CARDIAC OUTPUT Starling’s Law: ‘the output of the heart is equal to and determined by the amount of blood flowing into the heart, and may be increased or diminished within very wide limits according to the inflow” “Intrinsic control”
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“Extrinsic control” Extrinsic control
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Pulmonic Mitral Valve Aortic Valve Valve Tricuspid
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Aortic valve opens Aortic valve closes Mitral valve opens
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P pl P ra
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Cardiac Output Curve ) ( pl ra D HD P P C V = V Slope C D ED A S pl A S HS P C P P C V = ) ( Slope C S ES P - P pl A S pl ra D HS HD P C P P C V V SV = = ) ( f SV Q × = C = l A S P P C P C f Q pl D ra D C C
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) ( pl ra D HD P P C V = Cardiac Output Curve A S pl A S HS
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This note was uploaded on 08/27/2009 for the course BME 511 taught by Professor Khoo during the Fall '08 term at USC.

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Bme511_L1b_082709_final - Determination of steady state...

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