L1-Intro

L1-Intro - Zhong-Lin Lu Laboratory of Brain Processes...

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Zhong-Lin Lu Laboratory of Brain Processes (LOBES) Dana and David Dornsife Cognitive Neuroscience Imaging Center University of Southern California
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Overview The physics behind MRI The physiological basis of BOLD fMRI Basic experimental paradigms and data analysis Techniques Challenges and needs for novel data analysis and modeling techniques
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The physics behind MRI Light Source Object Reflection Lens Refraction Image The physics behind photographs
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1) Put subject in big static magnetic field [e.g., 3 T] 2) Transmit radio waves into subject [about 3 ms] 3) Turn off radio wave transmitter 4) Receive radio waves re-transmitted by subject Manipulate re-transmission with magnetic fields during this readout interval [10-100 ms: MRI is not a snapshot] 5) Store measured radio wave data vs. time Now go back to 2) to get some more data 6) Process raw data to reconstruct images The physics behind MRI The basic MRI procedure
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The physics behind MRI Spins within magnetic field
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Three relaxation mechanisms T1 – time constant for the recovery of the longitudinal magnetization. T2 – time constant for the reduction of the transverse magnetization due to spin- spin interaction. T2* -- time constant for the reduction of the transverse magnetization due to a combination of spin-spin interaction and non-homogeneity of the local field. The physics behind MRI
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This note was uploaded on 08/31/2009 for the course PSYC 425 taught by Professor Lu during the Spring '08 term at USC.

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L1-Intro - Zhong-Lin Lu Laboratory of Brain Processes...

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