WORKSHEET FOR MUTATIONS A

WORKSHEET FOR MUTATIONS A - WORKSHEET FOR MUTATIONS AND...

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WORKSHEET FOR MUTATIONS AND GENE REGULATION 1) Use the sentence of three-letter words as an analogy to demonstrate the effects of mutations on gene sequence. Name the types of mutations. Wild type "Normal Gene" THE ONE BIG FLY HAD ONE RED EYE TH Q ONE BIG FLY HAD ONE RED EYE THE ONE BIG THE ONE Q BI GFL YHA DON ERE DEY E THE ONE BIG HAD ONE RED EYE THE ONE BIG WET FLY HAD ONE RED EYE 2) Give 3 examples of known codons ( each coding for a different amino acid) that can be changed to a nonsense codon by a single base pair mutation. 3) The DNA and corresponding amino acid sequence of a portion of the wild-type trpA gene is shown below. The DNA sequence of three different trpA mutations is shown directly below the corresponding region in the wild-type sequence. [The DNA sequence of the coding strand is shown -- i.e., TTG = UUG = Leu.] A) TTG CAG GGATTT GGT ATT TCC GCC CCG GAT CAG GTA AAA Leu Gln Gly Phe Gly Ile Ser Ala Pro Asp Gln Val Lys * B) TAG CAG GGA TTT GGT ATT TCC GCC CCG GAT CAG GTA AAA
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This note was uploaded on 09/01/2009 for the course BIO 311C taught by Professor Satasivian during the Fall '08 term at University of Texas at Austin.

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WORKSHEET FOR MUTATIONS A - WORKSHEET FOR MUTATIONS AND...

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