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Unformatted text preview: Non-Competitive Inhibition: Vmax' = Vmax/(1 + [I]/Ki) To calculate the Ki for inhibitors A and B, use one of these 2 equations and the kinetic constants for the uninhibited reaction (ie Km and Vmax), along the Km' and Vmax' obtained in the presence of each inhibitor. For the inhibitors, use the concentration of inhibitor s in the calculation of Ki; for inhibitor A, [I] = 5 mM; for inhibitor B, [I] = 0.1 mM. 3. For more pratice, do problem 4(a), shown below. Problem 4(a) is taken from Voet & Voet, last year's textbook. More practice problems will be given in the form of problems from previous exams. Wilbur H. Campbell, 1995; firstname.lastname@example.org...
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This note was uploaded on 09/02/2009 for the course BIO BL 401 taught by Professor Wilbur during the Spring '07 term at Michigan Technological University.
- Spring '07