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2-6 evolution of gene families

2-6 evolution of gene families - EVOLUT IO N OF GENE FAM I...

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EVOLUTION OF GENE FAMILIES LIFE 24.2.4 – 24.2.5 & provided reading 24.2.4 New functions can arise by gene duplication - Gene duplication is another way in which proteins can acquire new functions. When a gene is duplicated, one copy of that gene is potentially freed from having to perform its original function. The identical copies of a duplicated gene can have any one of 4 different fates: Both copies of the gene may retain their original function (which can result in a change in the amount of gene product that is produced by the organism ). Both copies of the gene may retain the ability to produce the original gene product, but the expression of the genes may diverge in different tissues or at different times of development . One copy of the gene may be incapacitated by the accumulation of deleterious substitutions and become a functionless pseudogene . One copy of the gene may retain its original function, while the second copy accumulates enough substitutions that it can perform a different function.
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