neuron death - survived; 2. A key family member promoting...

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Many motor neurons die during normal development Fig 10.34 Motor neuron death is normal part of development in the chick spinal cord Exp: Removing leg bud; Grafting a leg bud; Due to programmed cell death.
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Fig 10.35 Refinement of muscle innervation by neural activity Muscle activation by neurons promote the death of other neurons.
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Many motor neurons die during normal development Due to programmed cell death. 1. Curare, the drug, blocks neuromuscular signal transmission, more motor neurons
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Unformatted text preview: survived; 2. A key family member promoting neuronal apoptosis during development is Bax . Bax-/- mice have increased number of motor neurons in face. Neuronal cell death and survival involve both intrinsic and extrinsic factors NGF: nerve growth factor: neurotrophins The receptor for the neurotrophins are RTK: Trk Different types of neuron require different neurotrophines for their survival...
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This note was uploaded on 09/03/2009 for the course BIO 503 taught by Professor Z.zyang during the Fall '09 term at Nanjing University.

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neuron death - survived; 2. A key family member promoting...

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