neuron migration

neuron migration - Neuronal migration Fig 10.19 Neurons...

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Neuronal migration Fig 10.19 Neurons make precise connections with their targets. Connections between neurons and their target cells are established by axonal outgrowth, guided by the movement of the axon tip (growth cone). Often, the initial set of relatively non-specific synaptic connections is then refined to produce a more precise pattern of connectivity.
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Fig 10.20 A developing axon and growth cone The growth cone controls the path taken by the growing axon The extension and extraction of filopodia involves the assembly and disassembly of the actin cytoskeleton. (Ras-related GTPases: Rho---stop extension, Rac and Cdc42--- extension) The growing membrane is provided by the intracellular vesicles, which fuse with the plasma membrane .
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Fig10.21 Axon-guidance mechanisms Axon growth cones are guided by two main types of cue--- attractive and repulsive. Extracellular matrix
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Motor neurons from the spinal cord make muscle-specific connections
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This note was uploaded on 09/03/2009 for the course BIO 503 taught by Professor Z.zyang during the Fall '09 term at Nanjing University.

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neuron migration - Neuronal migration Fig 10.19 Neurons...

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