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MCDB428lect07 - MCDB 428 Lecture 6 Wednesday Today's...

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Lecture 6: Wednesday January 16, 2008 Today’s Outline Membrane Potential revisited Protein Targeting Cytosolic ribosomes ER-associated ribosomes Signal-hypothesis ER signal peptide Presequence, transit peptide Nuclear Localization sequence ER targeting and protein translocation Elements of the translocon Co-translational translocation Post-translational translocation Type I-III proteins GPI-anchored proteins MCDB 428
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