Lecture 25 Mendelian Genetics Part I Slides

Lecture 25 Mendelian Genetics Part I Slides - Intro. to...

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Unformatted text preview: Intro. to Mendelian genetics Chap. 14 6 th ed; pp. 247-252 7 th ed; pp. 251-256 8 th ed; pp. 262-267 Review protein structure 6 th ed; pp 71-80 7 th & 8 th ed; pp. 77-83 Proteins: amino acid chains fold into HUGE variety of structures or Proteins: different structure allow HUGE diversity of functions (enzymes, receptors, cytoskeleton, etc...) PROTEINS ARE KEY!! DNA; stores, transmits hereditary information DNA codes for protein Gene = DNA that specifies (codes for) amino acids in 1 protein Many genes in 1 chromosome Gene 1 Gene 2 Gene 3 DNA in a chromosome Homologous chromosomes: almost identical; same genes with slight changes Alleles = different versions of the same gene Different alleles code for proteins with slightly different amino acid sequences. This can affect their activity! (Ser and Ala are amino acids.) Different forms of the same proteins- coded for by different alleles of the same genes- cause the variation between individuals. Example: hemoglobin. All humans have the hemoglobin gene. Most people have the same allele. A few people have a different allele (1 aa different!) and get sickle cell disease. Diploid cells contain pairs of homologous chromosomes. chromosomes....
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Lecture 25 Mendelian Genetics Part I Slides - Intro. to...

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