lecture_2__05 - DNA structure: Each strand of DNA is a...

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DNA structure: Each strand of DNA is a polymer composed of repeating units of nucleotides A nucleotide consists of a base, a deoxyribose sugar, and a phosphate each DNA strand has directionality; the direction is determined by the orientation of the sugar in relation to the phosphate backbone. The sugar is connected to the adjacent phosphates at the 3rd and the 5th carbon atoms of the pentose ring. Thus, every DNA strand has a 5’ end and a 3’ end. P P 1 2 3 4 5 base phosphate Fig. 16.3
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Fig. 16.6 There are 4 types of bases in DNA: adenine (A),thymine (T), guanine (G), and cytosine (C) A and G are purines , T and C are pyrimidines The bases are held together in double- stranded DNA by hydrogen bonds A pairs with T; G pairs with C there are 2 hydrogen bonds in a A-T basepair, and 3 hydrogen bonds in a G-C base pair. For this reason, G-C base pairs are kinetically more stable than A-T base pairs The bases in DNA:
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Figure 16.5 Each strand of DNA will spontaneously associate with its complementary strand, dictated by the sequence of the bases in each strand
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This document was uploaded on 09/06/2009.

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lecture_2__05 - DNA structure: Each strand of DNA is a...

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