lecture_7__05 - Translation: translation converts the...

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Translation: Fig. 17.4 translation converts the information contained in the nucleic acid of a gene (DNA, then transcribed into RNA) into a linear chain of amino acids. The genetic code links the nucleic acid sequence to the amino acid sequence. For each codon there exists a specific RNA molecule (tRNA ) that recognizes the codon sequence in the mRNA and is also bound to the corresponding amino acid. ..
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tRNA structure: the appropriate amino acid is covalently attached to the tRNA at the 3’ end the anticodon of the tRNA base-pairs with the mRNA while bound simulataneously to the ribosome , the large protein-RNA multisubunit complex that catalyzes protein synthesis Fig. 17.13 (5’) -U-U-C- (3’) mRNA
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aminoacyl-tRNA synthetases are responsible for joining the correct amino acids to the corresponding tRNA’s. There are 20 different types of these enzymes in cells, one for each amino acid. Fig. 17.14 http://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb2/part1/trna.htm
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Crystal Structure of the Ribosome at 5.5 Å Resolution Marat M. Yusupov, Gulnara Zh. Yusupova, Albion Baucom, Kate Lieberman,
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lecture_7__05 - Translation: translation converts the...

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