Lecture 18 (web)

Lecture 18 (web) - Final Final ESSENTIALS ESSENTIALS Posted...

Info iconThis preview shows pages 1–9. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Final Final ESSENTIALS ESSENTIALS Posted Posted Final Review Sessions Final Review Sessions June 4 (123 June 4 (123 Sci Sci Lec Lec , 5 , 5-- 7 pm) 7 pm) June 5 (1001 June 5 (1001 Giedt Giedt Hall, 5 Hall, 5-- 7 pm) 7 pm) Regrades Regrades (2. MT) due by TUE (June 2) (2. MT) due by TUE (June 2) Lecture 18 Lecture 18 Last co Last co-- factors factors : Tetrahydrofolate ( THF THF ) and S-Adenosylmethionine ( SAM SAM ) Some amino acid reactions amino acid reactions Synthesis of nucleotides nucleotides Nitrate/Nitrogen Assimilation (Plants, Microorganisms) Nitrate/Nitrogen Assimilation (Plants, Microorganisms) Glutamine Glutamate Ammonia (NH 4 + ) Gln Synthetase Glu Synthase Glutamate Amino Acids Aminotransferases Proteins Peptides Nucleotides Co-factors other Nitrate (NO 3- ) Dinitrogen (N 2 ) Ammonia (NH 4 + ) NAD(P)H NAD(P)H ATP, NAD(P)H ATP, NAD(P)H Sulfur Assimilation (Plants, Microorganisms) Sulfur Assimilation (Plants, Microorganisms) Cysteine Sulfate (SO 4 2- ) ATP, ATP, Ferredoxin Ferredoxin (red) (red) Serine Serine Cysteine Methionine Homoserine Homoserine N 5 Methyl Methyl-THF THF Essential Amino Acid Essential Amino Acid Co Co-- factors of Carbon Transfer factors of Carbon Transfer Coenzyme A Acetyl- and acyl- groups Thiamine pyrophosphate (TPP) C2-aldehyde/keto groups Biotin Activated CO 2 Tetrahydrofolic Tetrahydrofolic acid acid (THF) (THF) C1 groups of C1 groups of different oxidation states different oxidation states S-Adenosylmethionine Adenosylmethionine (SAM) (SAM) Methyl (CH Methyl (CH 3-) group ) group HN N N N O H 2 N H CH 2 N H C O H N CH CH 2 CH 2 COO- COO- Folic Acid and Tetrahydrofolic acid (THF) Pteridine ring (6-methyl pterin) p-Amino benzoic acid Glutamate FOLIC ACID 7 6 9 10 8 5 p. 96 THF: Coenzyme of C1 THF: Coenzyme of C1-Transfer Transfer NADPH + H+ NAD+ NADPH + H+ NADP+ 7,8-Dihydrofolic Acid (DHF) HN N NH H N O H 2 N H CH 2 N H 7 6 9 10 8 5 H H REST 5,6,7,8-Tetrahydrofolic Acid (THF) Dihydrofolate reductase THF is a carrier of C1 units at different oxidation states Folic Acid p. 96 p. 97 HN NH 5 6 9 10 HN N 5 6 9 10 N NH N NH 5 10 ATP ADP + Pi CH O N 10 formyl THF Ser Gly PLP CH 2 OH C H 2 N N N 5 N 10 methenyl THF C H N N NADPH + H + NADP + NADPH + H + NADP +...
View Full Document

This note was uploaded on 09/06/2009 for the course BIS 103 taught by Professor Abel during the Spring '08 term at UC Davis.

Page1 / 30

Lecture 18 (web) - Final Final ESSENTIALS ESSENTIALS Posted...

This preview shows document pages 1 - 9. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online