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Unformatted text preview: pathomimetic side effects. Inhaled and systemic corticosteroids may be used in COPD. They improve symptoms but do not slow decline in lung function. Prednisone (30-40 mg) may be given for 10-14 days. Oral theo-phylline (5 mg/kg loading dose followed by 5 mg/kg/day divided every 8-12 hours) is a third line agent for treating COPD who do not achieve adequate symptom control with anticholinergics, beta-adrenergic agonists, and inhaled corticosteroid therapy. Antibiotics are prescribed to outpatients to treat and acute exacerbation, to treat acute bronchitis, and to prevent acute exacerbations of chronic bronchitis. Current antibiotics proven to be more effective than older therapies include macrolides (azithromycin 500 mg followed by 250 mg daily for 5 days), fluoroquinolones (ciprofloxacin 500 mg every 12 hours), and amoxicillin-clavulanate (875/125 mg every 12 hours). All patients with COPD should receive influenza virus each year and a pneumococcal vaccine every 5 to 7 years....
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- Spring '09